Figure 7
From: The contribution of peroxynitrite generation in HIV replication in human primary macrophages
Electron microscopy of untreated or MnTBAP-treated HIV-1 infected macrophages. Untreated macrophages show accumulation of many mature particles, at different stages of maturation, in cytoplasmatic vacuoles and in the extracellular space. By contrast in MnTBAP (30 μM) treated macrophages no viral particles are found. This observation support the hypothesis that MnTBAP treatment is able to prevent enveloped and unenveloped virions production.