Figure 2
From: HIV-1 replication in cell lines harboring INI1/hSNF5 mutations
Analysis of particle production and infectivity in MON cells: A. Graphic representation of p24 antigen release (pg/ml) in the culture supernatants of 293T (â– ) and MON (â–¡) cells transfected with three plasmid based HIV-1 vectors (average of 3 independent experiments). B. Graphic representation of infectivity of virions, normalized for p24, produced in either 293T (â– ), or MON (â–¡). Both 293T and MON cells were infected with these two sets of virions (average of 3 independent experiments). C. Schematic representation of 2 blocks in HIV-1 replication in MON cells. 1st block exists at the level of virus particle production and the 2nd block exists at the level of infectivity. D. Schematic representation of a block in HIV-1 replication in STA-WT1 cells at the level of virus particle production.