Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency

Retrovirology

Table 2 Differential gene expression obtained for NCoA3 mRNA in ACH-2 cells treated or not with NaB.

Gene	Probe set Name ^a	ACH-2 Signal ^b	ACH-2 Detection p-value ^c	ACH2NaB Signal	ACH2NaB Detection p-value	ACH2NaBvsACH2 Signal log₂ ratio ^d	ACH2NaBvsACH2 Change p-value ^e
NCoA3	207700_s_at	43.3	0.001953	99.6	0.001221	1.2	0.000241
	209060_x_at	34.5	0.01416	72.9	0.001953	1	0.000273
	209061_at	65.8	0.000732	82.6	0.000732	1.6	0.005409
	209062_x_at	20	0.466064	76.7	0.095215	2	0.000114
	211352_s_at	2.7	0.5	37	0.030273	3.8	0.004481

^aAffymetrix U133-A reference probe set.
^bSignal intensity of hybridization.
^cSignal detection p-value < 0.048 for specific hybridization.
^dSignal log₂ ratio > 1 for increased genes and < -1 for decreased genes.
^eChange p-value < 0.0001 for significant increased genes and 1-change p-value > 0.9999 for significant decreased genes.

ISSN: 1742-4690