Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency

Retrovirology

Table 1 Differential gene expression obtained for NCoA3 and IRF8 mRNAs in U1 cells treated or not with NaB.

Gene	Probe set Name ^a	U1 Signal ^b	U1 Detection p-value ^c	U1NaB Signal	U1NaB Detection p-value	U1NaBvsU1 Signal log₂ ratio ^d	U1NaBvsU1 Change p-value ^e
NCoA3	207700_s_at	17.7	0.01416	98.9	0.000244	2.5	0.000035
	209060_x_at	16.9	0.171387	77.2	0.000244	2.3	0.000023
	209061_at	48.4	0.037598	166.4	0.000732	2.3	0.00002
	209062_x_at	6.3	0.72583	91.8	0.010742	4.5	0.000147
	211352_s_at	7.2	0.303711	68.6	0.00293	3.2	0.000101
IRF8	204057_at	707.9	0.000244	47	0.010742	-4	0.99998

^aAffymetrix U133-A reference probe set.
^bSignal intensity of hybridization.
^cSignal detection p-value < 0.048 for specific hybridization.
^dSignal log₂ ratio > 1 for increased genes and < -1 for decreased genes.
^eChange p-value < 0.0001 for significant increased genes and 1-change p-value > 0.9999 for significant decreased genes.

ISSN: 1742-4690