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Figure 2 | Retrovirology

Figure 2

From: The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness

Figure 2

Addition of M50I to R263K does not increase integrase strand-transfer activity. Strand-transfer activity and Vmax/1/2MaxProt of wild-type and mutant enzymes. A) Relative strand-transfer activity when varying protein concentration. B) Vmax values. C)1/2MaxProt values. D) Enzyme efficiency as determined by the division of Vmax by 1/2MaxProt. Error bars represent the standard errors of the means (SEM).

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Retrovirology

ISSN: 1742-4690

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