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Table 1 HIV-1 DNA integration sites and host-virus junction sequence

From: DNA damage enhances integration of HIV-1 into macrophages by overcoming integrase inhibition

Seq ID

Inhibitor

Chr

Locus

Strand

RefSeq gene

Insertion

Deletion

100902

DMSO

20

33371451

plus

NCOA6

-

-

100903

DMSO

17

35993714

minus

DDX52

-

-

100904

DMSO

3

156651874

minus

LEKR1

-

-

100906

DMSO

20

60900963

minus

LAMA5

-

-

100907

DMSO

3

19680267

minus

DLG1

-

-

100910

DMSO

4

150767744

plus

-

-

-

100912

DMSO

9

131400460

plus

WDR34

-

-

100914

DMSO

1

156020423

minus

UBQLN4

11bp (ACAGCAGTTAG)

37 bp

100916

DMSO

17

43551920

minus

PLEKHM1

-

-

100919

DMSO

20

2467413

minus

ZNF343

-

-

100921

DMSO

10

114725221

minus

TCF7L2

-

-

106501

DMSO

4

87017147

plus

MAPK10

-

-

106502

DMSO

2

98458616

minus

TMEM131

-

-

106505

DMSO

15

44399565

minus

FRMD10

-

-

106506

DMSO

2

197544261

plus

CCDC150

-

-

106510

DMSO

7

333212296

minus

BBS9

-

-

106513

DMSO

2

230499770

plus

DNER

-

-

106520

DMSO

17

38682989

plus

CR597260

-

-

106521

DMSO

19

17213409

minus

MY09B

-

-

106524

DMSO

6

33219360

plus

VPS52

-

-

100925

RAL

9

33033919

plus

DNAJA1

-

9 bp

100931

RAL

14

44024820

minus

-

-

20 bp

100937

RAL

2

102387409

plus

MAP4K4

9 bp (GACACTTAG0

-

100940

RAL

5

176735496

plus

MXD3

2 bp (AC)

-

100944

RAL

3

105267040

plus

-

21 bp (AATAAAAAGGTACAAATAGAC)

-

106525

RAL

14

87606685

minus

-

6 bp (TCATAA)

3 bp

106530

RAL

22

36006496

plus

MB

1 bp (A)

9 bp

106534

RAL

7

130544996

minus

CR618431

10 bp (TTGTAATTAC)

-

106537

RAL

1

63779999

minus

BC040309

16 bp (AAAGAAAAGGGGGGAC)

-

106538

RAL

3

190624485

minus

-

-

4 bp

106540

RAL

3

85084717

minus

CADM2

-

-

106542

RAL

18

40381428

minus

RIT2

2 bp (CA)

1 bp

106558

RAL

6

52427867

minus

TRAM2

-

-

106574

RAL

9

18460635

plus

-

9 bp (ACACCTAAT)

-

106582

RAL

1

6482403

minus

HES2

4 bp (GGAC)

-

106588

RAL

11

28954901

plus

-

4 bp (GGAC)

-

106596

RAL

7

92394729

plus

CDK6

4 bp (GGAC)

-

  1. HIV-1 DNA integratio sites were determined by LAM-PCR. LAM-PCR sequence were aligned to the human genome reference (GRCh37/hg19, Feb. 2009, UCSC). Chr, chromosome.