Figure 3

Treatment with auranofin increases the turnover of CD4⁺T-cell subsets and induces a partially selective apoptosis of the memory compartment. The cell subsets are identified by the expression of the surface markers CD28 and CD95 (naïve: CD28⁺ CD95^-; central and transitional memory: CD28⁺ CD95⁺; effector memory: CD28^- CD95⁺).