Skip to main content
Figure 5 | Retrovirology

Figure 5

From: The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to the small molecule maturation inhibitor 3-O-{3',3'-dimethylsuccinyl}-betulinic acid

Figure 5

The sequence of the CA-SP1 junction accounts for the differential sensitivity of HIV-1 and SIV to DSB. Viruses were harvested from transfected 293T cells, and equal quantities of p24 were used to inoculate cultures of activated primary CD4+ T cells. Cultures were maintained in the indicated concentrations of DSB and supernatants were monitored periodically for p24 production (A and B) or RT activity (C and D). Panel A: wild type HIV-1; Panel B: HIVm2; Panel C: wild type SIV; Panel D: SIVm3. Data shown are representative of duplicate growth curves. Similar results were obtained in two independent experiments.

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us